Abstract: Because of advancing space applications,such as Second Generation of Navigation System,Manned Spaceflight,Deep Space Missions,requirement on On-Board Computer(OBC) for higher performance has been arisen and normal OBCs are facing an upgrade of consume and rad-hard capability．Based on adaptive reconfiguration technology and System-on-Chip design method,this paper presented a reconfigurable tolerance method for MPSoC．High reliability and expansibility can be achieved at hardware level,which makes a great sense of space applications and military missions in future.After introducing the basic concepts of MPSoC and reconfigurable technique,several representative cases were presented as to show the development of reconfigurable processors．Then the basic infrastructure of our dynamic reconfigurable tolerance system was discussed．Moreover,tolerance strategy based on system degrading was presented in detail．A contrast analysis among single core,normal design and our method was provided．Besides,using leon3to implement the process elements,simulation validation of tolerance module efficiency was given out and the test results show the control mechanism works well．Finally,the future related works were discussed and the proposed reconfiguration tolerance method was concluded.