Computer Science ›› 2020, Vol. 47 ›› Issue (11A): 192-195.doi: 10.11896/jsjkx.191200070

• Computer Graphics & Multimedia • Previous Articles     Next Articles

Visualization of DNA Sequences of Two Kinds of Bacteria Under Firmicutes

DU Liu-yun, ZHENG Zhi-jie, ZHENG Hua-xian   

  1. School of Software,Yunnan University,Kunming 650500,China
  • Online:2020-11-15 Published:2020-11-17
  • About author:DU Liu-yun,born in 1995,master.Her main research interests includecomputerbiology science.
    ZHENG Zhi-jie,born in 1956,professor.His main research interests include computer biology science and quantum cryptography.
  • Supported by:
    This work was supported by the National Natural Science Foundation of China(K1020720),Overseas Senior Scholar Program of Yunnan Province(W811305),Science and Technology Program of Yunnan Province(KC1810123) and Key Project on Electric Information and Next Generation IT Technology of Yunnan (2018ZI002).

Abstract: In order to explore the relationship between biological layers,from complex bacterial communities to various species and genera,full sequence DNA sequencing has developed vigorously,and the need for visualization of scientific calculation data of various biological gene sequences has become increasingly urgent.The complementary symmetry between the double helix structure of DNA sequence and the complex structure of space is of great significance for exploring a large number of long DNA sequences.Starting from the core idea of “sequence determines structure and structure determines function”,this paper uses a measurement model and method based on variant value system to analyze and compare the complete DNA sequences of two kinds of bacteria,bacillus and Mycobacterium by using the method of combination of information technology and statistics,showing their two-dimensional characteristic distribution of DNA sequences.The visual form shows the similarities and differences between the two kinds of bacteria.Compared with the traditional bacterial visualization method,this method has the characteristics of low time complexity,good stability,strong intuition and easy to understand.A series of distribution diagrams are provided under different measurement reference options.

Key words: DNA, Gene sequence, Measurement model, Variant system, Visualization

CLC Number: 

  • TP399
[1] ZHU P X.Progress in microbial genome sequencing[J].Microorganisms and infection,1998(6):28-32.
[2] SHI C,SUN Y,XIAO B,et al.Research on the discovery of new antibiotics by genome data mining[J].Journal of pharmacy,2018(6):845-851.
[3] WANG J,GUO L,WU J S,et al.Current situation of bioinformatics research in the context of big data [J].Journal of Nanjing University of Posts and Telecommunications (Natural Science Edition),2017,37(4):62-67.
[4] LV H Q,HAO L L,LIU E H,et al.Research status and development trend of Hi-C based on bioinformatics [J/OL].Genetics:1-14.[2019-12-05].Http://kns.cnki.net/kcms/detail/11.1913.r.20191127.1304.006.html.
[5] WAN Z,ZHENG Z J E.Visualization of one-dimensional segmented measurement and distribution of DNA sequences [J].Journal of Yunnan University (Natural Science Edition),2013,35(S2).
[6] LI C,LIU H,CHU W W,et al.Two dimensional graphical representation of DNA sequence and its application [J].Journal of Bohai University (Natural Science Edition),2014,35(4):307-312,324.
[7] LI G L,RUAN Y,JGU R S,et al.Research on three-dimensional genomics [J].Science Bulletin,2014,59(13):1165-1172.
[8] TANG X C,ZHOU P P,QIU W Y.DNA sequence similarity analysis based on 4D graphical representation [J].Science Bulletin,2010,55(6):442-446.
[9] YANG C,YANG R F,CUI Y J,et al.Methods and applications of bacterial genome-wide association research[J].Genetics,2018,40(1):57-65.
[10] LI C,LIU H,CHU W W,et al.Two dimensional graphical representation and application of DNA sequence non degradation [J].Journal of Bohai University (Natural Science Edition),2014,35(4):307-312,324.
[11] ZHU T,ZENG D N,WHOLE P.Comparative analysis of bacterial community structure of skin between infant and mother[J].Microorganism and infection,2019,14(2):89.
[12] ZHENG J.Variant Construction From Theoretical Foundation toApplications[M].Springer Singapore,2019:56.
[13] JI Y.Research on Visualization Application of ECG data series based on VaR Measurement [D].Kunming:Yunnan University,2016.
[14] LENG L H,ZHENG Z J.Visualization of ECG sequence of sinus arrhythmia [J].Computer Science,2016,43 (S2):183-185.
[15] MAO Y,ZHENG J,LIU W.Mapping Whole DNA Sequence on Variant Maps[C]//IEEE/ACM International Conference.ACM,2017:1037-1040.
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