Abstract: Big data is becoming a hot topic in today’s society.Except of the IT field for its continuous exploration,it also continues to affect the economic and social progress.In the face of all walks of life to the big data hype,we should think seriously about the problems faced in the process of big data research and application.Domain knowledge is very important for a new technology,if we don’t know the field of domain knowledge in all walks of life,the development and application of them in different fields will face a lot of obstacles.This paper analyzed several aspects of the research and application of big data,and pointed out that big data processing involves data collection,data management,data analysis,data modeling and data application.Domain knowledge is the core of communication of data processing.As the key to the application of big data is data analysis,and data analysis is based on domain knowledge,the processing of big data must be through the field of domain knowledge to breakthrough.

Key words: Big data,Domain knowledge,System analysis