Abstract: In order to improve software reliability, software running in the event of the failure, rapid and accurate positioning of the point of failure has become a very meaningful study. Previous methods, Fault running sequence and the nearest running sequences to run the previous differences,in order to avoid selecting the first path caused by the recent success of recent blind-area exist,the impact of the increasing post search space,the paper introduced gene biology the principle of alignment of the nearest sequence to run not by editors to select from the comparison, but to processed through a consensus sequence. Experiments show that the method of fault location better.

Key words: Fault location, Sequence alignment, Running sequence, Consensus sequence