计算机科学 ›› 2022, Vol. 49 ›› Issue (11A): 211200097-6.doi: 10.11896/jsjkx.211200097

• 图像处理&多媒体技术 • 上一篇    下一篇

结合深度学习与改进的极限学习机的集成学习胸腺瘤CT图像预测方法

徐坤财1, 冯宝2, 陈业航2, 刘昱2, 周皓阳2, 陈相猛3   

  1. 1 桂林电子科技大学电子工程与自动化学院 广西 桂林 541004
    2 桂林航天工业学院电子信息与自动化学院 广西 桂林 541004
    3 江门市中心医院医学影像智能计算及应用实验室 广东 江门 529000
  • 出版日期:2022-11-10 发布日期:2022-11-21
  • 通讯作者: 陈业航(1535601070@qq.com)
  • 作者简介:(xkc1009@163.com)
  • 基金资助:
    国家自然科学基金项目(81960324);广西自然科学基金面上项目(粤桂联合基金项目)(2021GXNSFAA075037)

Thymoma CT Image Prediction Method Based on Deep Learning and Improved Extreme Learning Machine Ensemble Learning

XU Kun-cai1, FENG Bao2, CHEN Ye-hang2, LIU Yu2, ZHOU Hao-yang2, CHEN Xiang-meng3   

  1. 1 School of Electronic Engineering and Automation,Guilin University of Electronic Technology,Guilin,Guangxi 541004,China
    2 School of Electronic Information and Automation,Guilin University of Aerospace Technology,Guilin,Guangxi 541004,China
    3 Medical Image Intelligent Computing and Application Laboratory,Jiangmen Central Hospital,Jiangmen,Guangdong 529000,China
  • Online:2022-11-10 Published:2022-11-21
  • About author:XU Kun-cai,born in 1997,postgra-duate.His main research interests include application of machine learning in medical images and so on.
    CHEN Ye-hang,born in 1993,master.His main research interests include machine learning technology and its application in biomedical signal processing.
  • Supported by:
    National Natural Science Foundation of China(81960324) and General Project of Guangxi Natural Science Foundation(Guangdong Guangxi Joint Fund Project)(2021GXNSFAA075037).

摘要: 针对胸腺瘤患者术前危险程度的预测问题,提出了结合深度学习与改进的极限学习机的集成学习计算机辅助分析方法。首先,将胸腺瘤CT图像通过小波多尺度变换到不同的尺度下并计算小波能量图,以增加图像信息的丰富性和多样性;其次,利用小波能量图训练卷积神经网络模型,并利用卷积核提取小波能量图中与任务相关的特异性深度特征;最后,基于改进的极限学习机为基分类器训练具有差异性的子模型并构建集成学习分类模型,以提高模型的稳定性和预测精度。多中心实验结果表明,所提方法有较好的泛化性能和稳定性,3个验证集的AUC分别为0.833,0.771,0.784。

关键词: 胸腺瘤, 小波变换, 卷积神经网络, 极限学习机, 集成学习

Abstract: To predict the risk of thymoma patients before operation,a computer-aided analysis method combining deep learning and extreme learning machine ensemble learning is proposed.Firstly,the CT image of thymoma is transformed to different scales by wavelet multi-scale transform,and the wavelet energy map is calculated to improve the richness and diversity of image information.Secondly,the convolution neural network model is trained by wavelet energy map,and the specific depth features related to tasks in wavelet energy map are extracted by convolution kernel.Finally,the differentiated training subsets are trained based on the improved limit learning machine,and ensemble learning is constructed to improve the stability and prediction accuracy of the model.Based on multicenter experiments,the results show that the proposed method has good generalization performance and stability.The AUCs of the three verification sets are 0.833,0.771 and 0.784 respectively.

Key words: Thymoma, Wavelet transform, Convolutional neural network, Extreme learning machine, Ensemble learning

中图分类号: 

  • TN911.73-34
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