关键词: 蛋白质关系网络，网络可视化，图聚类，JUNG工具包

Abstract: Research on protein-protein interaction (PPI) network has become a hot spot in the biomedical domain. With analysis and clustering application on PPI network, researchers detect complexes for a better understanding of cellular organizations. Visualizing PPI network in analyzing process can intuitively present the organization of the network,which makes easy comparison of clustering methods and promotes researches on PPI network. We designed and implemented a PPI network visualization system with JUNG, a network modeling and visualization library. We also integrated several effective graph clustering algorithms into the system, and implemented a protein complex detection method based on protein function annotation. The original network and clusters can be navigated conveniently in two-dimensional network views.

Key words: PPI network, Network visualization, Graph clustering, JUNG toolkit