Abstract: Immunodominance clone select algorithm is a new kind of immunodominance algorithm with strong local and global search ability.Combining it with cultural algorithm,we put forward a new immunodominance clone cultural algorithm.It can make use of transcendental knowledge to guide the evolution of species.We designed a new dynamic acceptance function to promote knowledge updating in cultural algorithm and increase the search capability of the algorithm.Immunodominance clone cultural algorithm was used in nuclear parameter optimization of support vector machine (SVM) for constructing the good performance classifier.The results of Wine dataset classification and fault diagnosis of TE reflect that immunodominance clone cultural algorithm can search the nuclear parameter optimization of SVM accurately.It raises the accuracy of fault diagnosis and has better spread value.

Key words: Immunodominance clone select algorithm,Cultural algorithm,SVM,Fault diagnosis