Abstract: It might be a sign of pathology when an organ of a person appears more asymmetric than others. Based on mathematically asymmetric theory, an improved asymmetric computing model of 3-D medical image was presented, and a numerical method and computing framework were studied. The method can be used to diagnose cholesteatomatous chronic otitis media by numerical experiments. Compared with the doctors' diagnosis, the ratio of the numerical diagnosis of patients' cholesteatoma confidence is up to 98 percent by testing of T distribution method. The asymmetry computing model has both measurable and objective properties so that it can be extended to other computer-assisted diagnosis related to medical asymmetry.

Key words: Asymmetry computing, Affine transformation, Cholesleatoma diagnosis, Pyramid algorithm, Test of T distribution