Abstract: Artificial metabolic algorithm(AMA) model was built based on physiological metabolic functions in organism. Multi-step catalytic reaction kinetics model was obtained by analysis concentration difference between substrate and product. Searching optimization model for traveling salesman probl}m(TSP) based on concentration difference was established by using analogous analysis between city network and metabolic network. One real example states that optimination programming for traveling salesman problem(TSP) can be implemented efficiently through artificial metabolic algorithm.

Key words: Artificial metabolic algorithm(AMA) , Traveling salesman problem(TSP) , Metabolic operator, Enzyme