Abstract: With the development of the researches and improvement of experiment on optical molecular imaging, a simulation platform, which can realize the light propagation in tissues and frecspace, is urgently required by the researchers.This paper introduced a platform MOSE(Molecular Optical Simulation Environment) which integrates the forward simulation of three different modalities of optical molecular imaging. Based on a uniform framework,the platform provided the simulation of light propagation in turbid media and frecspace combined with the functions of graphic visualization and data analysis. The structure design of the platform, simulation algorithms, graphic visualization and some simulation examples were provided in details. The experiment shows that the researchers could efficiently implement the simulation experiment and data analysis in the study of optical molecular imaging through the platform.

Key words: Optical molecular imaging, Light propagation, Monte carlo, Object orientation, Simulation platform