Abstract: Most of the traditional virus immunization strategics arc based on global network topology information, how- ever, most real-life complex networks are known to us with only the local topology information. In view of that scale- free property exists in many real-life complex networks, the virus spreading with shortest path immunization strategy based on local topology information in scalcfrec complex evolving network was studied. I}his article used the mean-field theory to build a virus spreading model in scale-free network introducing a immunization strategy based on shortest path and a key factor; individual resistance. After comparing the efficiency of random immunization, target immunization and shortest path immunization for virus spreading in scale-free complex networks, the result indicates that the immuniza- lion strategy based on shortest path has important effectiveness.

Key words: Complex network, Virus spreading, Individual resistance, Immunization strategy, Local topology