Abstract: This paper focused on the requirements of describing particle size and distribution uniformity of nuclear chromatin in image analysis of cervical cytology,proposed a mathematical morphology-based particle analysis method to describe particle size of nuclear chromatin.In this method,the distribution uniformity of chromatin is described using the variance of color depth of each radiation line whose starting point is the centroid of nuclei.It described two specific chromatin feature extraction algorithm.The experiments prove that the proposed chromatin described features can be more effective nuclear chromatin image characteristics.

Key words: Mathematical morphology,Particle analysis,Cytology,Chromatin features