Abstract: In recent years,with the widespread adoption and rapid development of technologies such as the Internet,big data and artificial intelligence,scientific research management is gradually shifting from traditional models to new paradigms driven by data,informatization and intelligence.This transformation has made traditional information system architectures increasingly inadequate to cope with the demands of massive data exchange,data sharing and data security.This paper takes the information system architecture of the National Natural Science Foundation of China(hereinafter referred to as “the NSFC”) as an example to explore its development and evolution directions.Faced with the advancement of science fund reforms in the new era,the existing information systems of the NSFC are facing numerous challenges in terms of network and data security,enhancement of intelligent service levels,and optimization of system development and management efficiency.This paper first introduces the current application status of two traditional information system architectures in the NSFC,and then conducts an in-depth analysis of the challenges faced by the existing information systems from four aspects:the growth of business volume and the number of bu-siness systems,the replacement of information technology with domestic innovation,intelligent services,and data management.Finally,it provides thoughts on the subsequent development of the information system architecture from two dimensions:data ma-nagement and microservices.

Key words: Informationization, Information system architecture, Data-centric architecture, Data management, Microservice